# CJC-1295 Ipamorelin References: The Cited Literature, With DOIs and PMIDs

> CJC-1295 Ipamorelin references: every study cited across this site, with authors, journal, year, DOI, and PubMed links — the full peer-reviewed source list.

Every quantitative claim on this site maps to one of these peer-reviewed sources, with DOI and PubMed links.

## How to read this list

Every numbered citation [N] used across the CJC-1295 Ipamorelin pages corresponds to an entry below, with authors, journal, year, and a DOI or PubMed link where available. The list spans the foundational synergy work (Bowers 1990; Cunha 2002), the CJC-1295 human pharmacokinetics (Teichman 2006; Ionescu 2006), the DAC chemistry (Jetté 2005), ipamorelin's defining selectivity study (Raun 1998), the GH-secretagogue safety review (Sigalos 2018), and class-level and read-across evidence (the TZP-101 postoperative-ileus studies; the tesamorelin meta-analysis). Where a study used a related peptide rather than the fixed blend, that is stated in the body text that cites it — the references here are the primary sources, read in context on the page that uses them.

## References

[1] Teichman SL, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. https://pubmed.ncbi.nlm.nih.gov/16352683/
[2] Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61. https://pubmed.ncbi.nlm.nih.gov/9849822/
[3] Bowers CY, et al. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab. 1990;70(4):975-82. https://pubmed.ncbi.nlm.nih.gov/2108187/
[4] Cunha SR, et al. Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3',5'-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors. Endocrinology. 2002;143(12):4570-82. https://pubmed.ncbi.nlm.nih.gov/12446584/
[5] Jetté L, et al. Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology. 2005;146(7):3052-8. https://pubmed.ncbi.nlm.nih.gov/15817669/
[6] Sigalos JT, et al. The Safety and Efficacy of Growth Hormone Secretagogues. Sex Med Rev. 2018;6(1):45-53. https://pubmed.ncbi.nlm.nih.gov/28400207/
[7] Badran AS, et al. Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials. Obes Res Clin Pract. 2026;20(1):2-12. https://pubmed.ncbi.nlm.nih.gov/41545261/
[8] Memdouh S, et al. Advances in the detection of growth hormone releasing hormone synthetic analogs. Drug Test Anal. 2021;13(11-12):1871-1887. https://pubmed.ncbi.nlm.nih.gov/34665524/
[9] Ionescu M, et al. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-7. https://pubmed.ncbi.nlm.nih.gov/17018654/
[10] Ho KY, et al. Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J Clin Invest. 1988;81(4):968-75. https://pubmed.ncbi.nlm.nih.gov/3127426/
[11] Fraser GL, et al. Effect of the ghrelin receptor agonist TZP-101 on colonic transit in a rat model of postoperative ileus. Eur J Pharmacol. 2009;604(1-3):132-7. https://pubmed.ncbi.nlm.nih.gov/19121631/
[12] Venkova K, et al. Prokinetic effects of a new ghrelin receptor agonist TZP-101 in a rat model of postoperative ileus. Dig Dis Sci. 2007;52(9):2241-8. https://pubmed.ncbi.nlm.nih.gov/17436082/
[13] Halmos G, et al. Growth hormone-releasing hormone receptor (GHRH-R) and its signaling. Rev Endocr Metab Disord. 2025. https://pubmed.ncbi.nlm.nih.gov/39934495/
[14] Gouda M, et al. The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus. Anim Reprod Sci. 2024;266:107550. https://pubmed.ncbi.nlm.nih.gov/38996787/

---

A mechanism-first reading of the CJC-1295 and ipamorelin record — two receptors, two timescales, every figure logged to its study and the untested fixed blend kept in plain view; no clinic behind the console and nothing here dosed, stacked, prescribed, or sold.